Now, on the Task Manager window, select File located on the above-left side.Press Ctrl + Alt + Del and you will be redirected to a new blue page.You can try launching the Command Prompt from the task manager. If you are unable to launch CMD through the Cortana search because of the black screen. Let the verification complete, and then restart your system and check the error message of Personalized Settings Not Responding is still flashing or not.Enter the following command- sfc/scannow, and hit enter.Launch Command Prompt from the Cortana search box by typing CMD.To run SFC on your system, follow the below method: System File Checker is a utility tool used to repair damaged and corrupted files in a Windows installation. Once you complete this step, check whether the issue still persists. Navigate to Windows Explorer, and right-click it to restart.Launch Task Manager using the same steps used in Fix 2.Due to this Windows Explorer is unable to open and therefore you get an error message Windows 10 personalized settings not responding. Sometimes, Windows Explorer, while running in the background, gets stuck. Fix 3- Restart File Explorer Via Task Manager